iPPI-DB

Inhibitors of Protein-Protein Interaction Database
Protein Interaction database overview

Explore, search, filter and order the Protein Interaction database to find your ressources.

Overview
Interactive TMAP

Explore a graphical representation of pocket properties and pocket clustering within an interactive TMAP.

TMAP
Explore the Protein Interaction database
23238 Pockets in 3715 proteins of 519 organisms
23238 Pockets in 3715 proteins of 519 organisms
Search results

Search Pattern : P13010 , 2 result(s)

1jeq
Chain A P12956 Homo sapiens
Chain B P13010 Homo sapiens
3rz9
Chain A P52293 Mus musculus
Chain B P13010 Homo sapiens

First pdb is loaded below

1jeq
Structure of with partner X-ray repair cross-complementing protein 6 with partner X-ray repair cross-complementing protein 5
Note: Use your mouse to drag, rotate, and zoom in and out of the structure.
Pockets

The color gradient for the table is based on maximum and minimum PSI (Pocket Similarity Index) in the matrix. PSI is given when you mouseover a pocket name.

Table of descriptors for each pocket, detected by Volsite (Desaphy et al., 2012). Click on icon to see closest pockets, based on the Pocket Similarity Index. Pocket name is built with: pdb id / pocket's chain id | name / pocket number :: partner ligand id or chain id | name

0.00 1.00
Pockets
Type
Volume
NPR1
NPR2
Asphericity
Eccentricity
Rgyr
Spherocity Index
CA
CZ
N
O
OG
NZ
OD1
DU
T40
T40-50
T50-60
T60-70
T70-80
T80-90
T90-100
T100-110
T110-120
T120
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/1 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 1058 0.37 0.81 0.26 0.93 8.67 0.25 39.0 6.3 20.9 4.8 2.6 0.8 5.8 19.8 0.6 9.3 42.8 29.7 12.0 4.5 1.0 0.1 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/2 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 424 0.20 0.96 0.52 0.98 6.87 0.22 34.7 9.9 20.0 4.2 3.5 0.0 8.7 18.9 0.5 9.2 30.4 27.8 20.8 9.9 1.4 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/3 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 749 0.24 0.91 0.45 0.97 7.35 0.21 30.3 0.0 6.8 4.3 11.3 18.2 9.9 19.2 0.5 9.7 35.4 34.3 17.8 2.3 0.0 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/4 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 414 0.52 0.88 0.13 0.86 4.65 0.49 36.7 20.0 14.7 2.4 1.2 0.0 9.2 15.7 0.2 7.0 34.5 41.8 13.8 2.7 0.0 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/5 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 182 0.65 0.79 0.06 0.76 3.21 0.54 62.6 6.6 8.2 7.7 0.0 0.5 2.2 12.1 1.1 5.5 19.2 21.4 15.4 13.7 17.0 6.6 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/6 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 171 0.20 0.95 0.52 0.98 3.84 0.21 51.5 4.7 4.1 1.8 20.5 0.6 0.0 17.0 0.6 11.7 32.2 29.2 17.0 9.4 0.0 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/7 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 167 0.41 0.96 0.24 0.91 3.19 0.46 53.9 0.0 14.4 9.0 1.8 0.0 0.0 21.0 1.2 11.4 37.7 24.0 12.0 12.6 1.2 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/8 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 141 0.28 0.94 0.38 0.96 3.41 0.30 34.0 6.4 36.9 3.5 5.0 0.0 0.0 14.2 0.0 9.9 43.3 32.6 12.1 2.1 0.0 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/9 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 125 0.21 0.98 0.50 0.98 3.29 0.26 58.4 17.6 3.2 0.8 0.0 0.0 9.6 10.4 1.6 13.6 32.8 28.8 17.6 5.6 0.0 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/11 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 119 0.42 0.78 0.22 0.91 3.03 0.27 69.7 0.0 14.3 15.1 0.0 0.0 0.0 0.8 0.8 5.9 31.1 33.6 16.8 11.8 0.0 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/12 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 111 0.35 0.89 0.29 0.94 3.18 0.32 52.3 9.9 18.0 2.7 2.7 0.0 0.0 14.4 0.0 9.9 52.3 33.3 4.5 0.0 0.0 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/14 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 100 0.39 0.80 0.24 0.92 2.84 0.26 56.0 24.0 0.0 0.0 4.0 0.0 0.0 16.0 0.0 14.0 42.0 34.0 8.0 2.0 0.0 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/18 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 73 0.33 0.83 0.32 0.95 2.68 0.22 64.4 23.3 2.7 1.4 1.4 0.0 0.0 6.8 0.0 9.6 49.3 27.4 12.3 1.4 0.0 0.0 0.0 0.0
1jeq /
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/24 ::
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 42 0.54 0.68 0.13 0.84 2.03 0.30 50.0 0.0 45.2 2.4 0.0 0.0 0.0 2.4 0.0 4.8 47.6 33.3 11.9 2.4 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/1 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 902 0.30 0.81 0.35 0.95 9.25 0.16 35.9 11.8 12.9 7.6 0.0 12.7 8.9 10.2 0.3 6.7 30.3 25.9 16.7 12.0 7.9 0.2 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/2 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 308 0.29 0.84 0.37 0.96 4.64 0.17 40.9 13.6 10.7 2.6 1.9 0.0 10.1 20.1 0.3 11.7 36.0 36.4 14.6 1.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/4 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 173 0.47 0.75 0.17 0.88 3.34 0.30 48.6 12.7 17.9 1.2 0.0 0.0 0.0 19.7 0.6 11.6 41.0 31.8 14.5 0.6 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/5 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 158 0.33 0.97 0.32 0.94 3.35 0.40 27.2 10.1 34.8 3.8 0.0 0.0 12.0 12.0 0.0 9.5 43.7 31.0 15.2 0.6 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/6 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 133 0.13 0.95 0.66 0.99 3.93 0.11 66.2 9.8 5.3 3.0 1.5 0.0 0.0 14.3 0.0 11.3 34.6 33.8 18.8 1.5 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/7 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 132 0.45 0.77 0.19 0.90 3.12 0.29 32.6 28.8 7.6 4.5 5.3 0.0 1.5 19.7 0.0 10.6 43.9 38.6 6.8 0.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/9 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 98 0.23 0.91 0.46 0.97 3.16 0.21 54.1 22.4 6.1 2.0 0.0 0.0 11.2 4.1 0.0 6.1 39.8 33.7 18.4 2.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/10 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 98 0.52 0.82 0.13 0.85 2.70 0.43 8.2 37.8 22.4 4.1 14.3 0.0 0.0 13.3 2.0 7.1 37.8 31.6 13.3 5.1 3.1 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/12 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 84 0.28 0.90 0.39 0.96 2.75 0.24 61.9 1.2 23.8 0.0 0.0 0.0 0.0 13.1 3.6 13.1 46.4 27.4 9.5 0.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/16 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 64 0.49 0.79 0.15 0.87 2.32 0.37 65.6 12.5 7.8 1.6 0.0 0.0 0.0 12.5 0.0 7.8 45.3 29.7 12.5 3.1 1.6 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/17 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 54 0.40 0.92 0.23 0.91 2.22 0.42 63.0 0.0 31.5 1.9 0.0 0.0 0.0 3.7 0.0 5.6 48.1 29.6 16.7 0.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/18 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 53 0.51 0.68 0.16 0.86 2.31 0.25 58.5 7.5 18.9 5.7 0.0 0.0 0.0 9.4 0.0 9.4 49.1 37.7 3.8 0.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/20 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 46 0.24 0.92 0.45 0.97 2.42 0.23 39.1 50.0 2.2 0.0 0.0 4.3 0.0 4.3 0.0 6.5 50.0 37.0 6.5 0.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/23 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 43 0.52 0.79 0.13 0.86 1.96 0.40 18.6 20.9 27.9 20.9 0.0 0.0 0.0 11.6 0.0 7.0 60.5 20.9 11.6 0.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/24 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 41 0.43 0.69 0.22 0.90 2.16 0.16 78.0 4.9 4.9 0.0 0.0 0.0 0.0 12.2 0.0 9.8 46.3 29.3 14.6 0.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/27 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 39 0.40 0.79 0.23 0.92 1.96 0.26 46.2 25.6 0.0 0.0 2.6 0.0 17.9 7.7 0.0 15.4 28.2 41.0 15.4 0.0 0.0 0.0 0.0 0.0
1jeq /
B | XRCC5
Query UniprotID in PIE Query UniprotID as iPPI-DB target
/29 ::
A | XRCC6
Query UniprotID in PIE Query UniprotID as iPPI-DB target
O 36 0.35 0.87 0.29 0.94 1.99 0.29 50.0 0.0 25.0 11.1 0.0 8.3 0.0 5.6 0.0 5.6 50.0 33.3 11.1 0.0 0.0 0.0 0.0 0.0