IPPI-DB Compounds list

carbohydrate binding

cytokine activity

glycosphingolipid binding

growth factor activity

interleukin-2 receptor binding

kinase activator activity

Ras guanyl-nucleotide exchange factor activity

drug binding

interleukin-2 binding

interleukin-2 receptor activity

DNA binding

E-box binding

protein complex binding

repressing transcription factor binding

RNA polymerase II core promoter proximal region sequence-specific DNA binding

transcription factor activity, sequence-specific DNA binding

transcription factor binding

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding

transcription coactivator activity

transcription cofactor activity

transcription factor activity, RNA polymerase II core promoter sequence-specific

structural molecule activity

coreceptor activity

enzyme binding

extracellular matrix structural constituent

glycoprotein binding

MHC class II protein binding

protein homodimerization activity

protein kinase binding

receptor activity

transmembrane signaling receptor activity

virus receptor activity

zinc ion binding

alpha-catenin binding

androgen receptor binding

cadherin binding

chromatin binding

estrogen receptor binding

I-SMAD binding

ion channel binding

kinase binding

nuclear hormone receptor binding

protein C-terminus binding

protein phosphatase binding

RNA polymerase II activating transcription factor binding

RNA polymerase II core promoter sequence-specific DNA binding

RNA polymerase II transcription factor binding

signal transducer activity

SMAD binding

transcription regulatory region DNA binding

bHLH transcription factor binding

identical protein binding

protein heterodimerization activity

TFIIB-class transcription factor binding

transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting

transcription factor activity, TFIIB-class binding

cell adhesion molecule binding

ICAM-3 receptor activity

metal ion binding

integrin binding

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

protease binding

SH3/SH2 adaptor activity

GTP binding

GTPase activity

cysteine-type endopeptidase inhibitor activity involved in apoptotic process

ubiquitin protein ligase activity

ubiquitin-protein transferase activity

ligase activity

p53 binding

SUMO transferase activity

ubiquitin protein ligase binding

ATP binding

chaperone binding

copper ion binding

core promoter sequence-specific DNA binding

damaged DNA binding

histone acetyltransferase binding

protein N-terminus binding

protein phosphatase 2A binding

protein self-association

receptor tyrosine kinase binding

RNA polymerase II regulatory region sequence-specific DNA binding

RNA polymerase II transcription factor activity, sequence-specific DNA binding

transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding

BH3 domain binding

channel activity

channel inhibitor activity

sequence-specific DNA binding

cysteine-type endopeptidase activator activity involved in apoptotic process

lipid binding

phospholipid binding

death receptor binding

protein channel activity

activating transcription factor binding

RNA binding

RNA polymerase II transcription coactivator activity

supercoiled DNA binding

aspartic-type endopeptidase activity

DNA-directed DNA polymerase activity

exoribonuclease H activity

RNA-directed DNA polymerase activity

RNA-DNA hybrid ribonuclease activity

ATP-dependent DNA helicase activity

nucleotide binding

microtubule binding

lysine-acetylated histone binding

RNA polymerase II core binding

histone binding

protein domain specific binding

heparin binding

semaphorin receptor activity

vascular endothelial growth factor-activated receptor activity

chemoattractant activity

growth factor binding

vascular endothelial growth factor receptor 1 binding

vascular endothelial growth factor receptor 2 binding

vascular endothelial growth factor receptor binding

placental growth factor-activated receptor activity

transmembrane receptor protein tyrosine kinase activity

VEGF-A-activated receptor activity

VEGF-B-activated receptor activity

extracellular matrix binding

fibronectin binding

neuropilin binding

platelet-derived growth factor receptor binding

receptor agonist activity

actin binding

JUN kinase binding

non-membrane spanning protein tyrosine kinase activity

protein kinase activity

protein tyrosine kinase activity

receptor binding

SH2 domain binding

urokinase plasminogen activator receptor activity

serine-type endopeptidase activity

double-stranded DNA binding

four-way junction DNA binding

protein binding, bridging

R-SMAD binding

Y-form DNA binding

AT DNA binding

histone methyltransferase activity (H3-K4 specific)

histone-lysine N-methyltransferase activity

unmethylated CpG binding

kappa-type opioid receptor binding

protein dimerization activity

immunoglobulin binding

interleukin-16 binding

interleukin-16 receptor activity

protein tyrosine kinase binding

disordered domain specific binding

5S rRNA binding

NEDD8 ligase activity

peroxisome proliferator activated receptor binding

ribonucleoprotein complex binding

scaffold protein binding

histone deacetylase binding

mRNA 3'-UTR binding

transcription factor activity, core RNA polymerase binding

14-3-3 protein binding

protein kinase B binding

protein phosphatase 2B binding

Hsp70 protein binding

BH domain binding

dynein complex binding

heat shock protein binding

GTPase activator activity

vascular endothelial growth factor binding

VEGF-C-activated receptor activity

RNA polymerase II distal enhancer sequence-specific DNA binding

transcription cofactor binding

transcription regulatory region sequence-specific DNA binding

GDP binding

GMP binding

LRR domain binding

protein-containing complex binding

guanyl-nucleotide exchange factor activity

Rho guanyl-nucleotide exchange factor activity

SH3 domain binding

methylated histone binding

dinucleotide insertion or deletion binding

DNA polymerase binding

DNA polymerase processivity factor activity

MutLalpha complex binding

purine-specific mismatch base pair DNA N-glycosylase activity

clathrin binding

GTPase binding

MDM2/MDM4 family protein binding

phosphoprotein binding

protein kinase C inhibitor activity

ATPase binding

beta-catenin binding

estrogen receptor activity

estrogen response element binding

nitric-oxide synthase regulator activity

nuclear receptor activity

steroid binding

TBP-class protein binding

transcription coactivator binding

nucleic acid binding

GTP-dependent protein kinase activity

RNA polymerase II C-terminal domain binding

RNA polymerase II CTD heptapeptide repeat kinase activity

nucleosomal DNA binding

acetyltransferase activity

cis-regulatory region sequence-specific DNA binding

histone acetyltransferase activity

MRF binding

peptide-lysine-N-acetyltransferase activity

transcription corepressor activity

ubiquitin ligase-substrate adaptor activity

Hsp90 protein binding

CD40 receptor binding

tumor necrosis factor receptor binding

hormone activity

thyroid hormone binding

receptor serine/threonine kinase binding

transmembrane receptor protein serine/threonine kinase activity

protein serine/threonine kinase activity

peptidase activity

cobalt ion binding

obsolete cofactor binding

Ran GTPase binding

tubulin binding

proton-exporting ATPase activity, phosphorylative mechanism

cullin family protein binding

alpha-actinin binding

calcium-activated potassium channel activity

calmodulin binding

ion channel activity

small conductance calcium-activated potassium channel activity

adenylate cyclase activator activity

adenylate cyclase binding

calcium channel inhibitor activity

calcium channel regulator activity

calcium ion binding

calcium-dependent protein binding

enzyme regulator activity

N-terminal myristoylation domain binding

nitric-oxide synthase binding

phosphatidylinositol 3-kinase binding

protein phosphatase activator activity

titin binding

type 3 metabotropic glutamate receptor binding

potassium channel activity

potassium ion leak channel activity

voltage-gated potassium channel activity

transferase activity

isomerase activity

AMP binding

protein kinase regulator activity

protein serine/threonine kinase activator activity

AMP-activated protein kinase activity

ARF guanyl-nucleotide exchange factor activity

histone methyltransferase activity

RNA polymerase II transcription corepressor binding

DNA-binding transcription repressor activity, RNA polymerase II-specific

histone demethylase activity

chromatin DNA binding

histone methyltransferase activity (H3-K27 specific)

primary miRNA binding

promoter-specific chromatin binding

protein-lysine N-methyltransferase activity

histone acetyltransferase regulator activity

ATPase activity

nuclear receptor binding

RNA polymerase I core promoter sequence-specific DNA binding

hemi-methylated DNA-binding

methyl-CpG binding

nucleosomal histone binding

histone methyltransferase activity (H3-K9 specific)

telomeric DNA binding

ubiquitin modification-dependent histone binding

antigen binding

immunoglobulin receptor binding

1-phosphatidylinositol-3-kinase regulator activity

ErbB-3 class receptor binding

insulin binding

insulin receptor binding

insulin receptor substrate binding

insulin-like growth factor receptor binding

neurotrophin TRKA receptor binding

phosphatidylinositol 3-kinase regulator activity

phosphatidylinositol 3-kinase regulatory subunit binding

phosphotyrosine residue binding

transmembrane receptor protein tyrosine kinase adaptor activity

alpha-tubulin binding

CD4 receptor binding

CD8 receptor binding

ephrin receptor binding

growth factor receptor binding

peptide hormone receptor binding

T cell receptor binding

tau protein binding

tau-protein kinase activity

type 5 metabotropic glutamate receptor binding

phosphorelay sensor kinase activity

protein histidine kinase activity

magnesium ion binding

phosphorelay response regulator activity

ATPase regulator activity

cysteine-type endopeptidase activity

DEAD/H-box RNA helicase binding

keratin filament binding

MHC class I protein binding

GO_0017137

RNA helicase activity

RNA-directed 5'-3' RNA polymerase activity

scavenger receptor binding

serine-type peptidase activity

STAT family protein binding

Toll-like receptor 2 binding

translation initiation factor binding

beta-2-microglobulin binding

co-receptor binding

transferrin receptor binding

acetylcholine-gated cation-selective channel activity

toxin activity

indole-3-acetonitrile nitrile hydratase activity

transition metal ion binding

apolipoprotein A-I receptor binding

GBD domain binding

GTP-dependent protein binding

mitogen-activated protein kinase kinase kinase binding

thioesterase binding

serine-type endopeptidase inhibitor activity

phospholipase A2 activity

phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)

phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)

DNA-directed 5'-3' RNA polymerase activity

N-acetylmuramoyl-L-alanine amidase activity

alpha-amylase inhibitor activity

alpha-amylase activity

alpha-amylase activity (releasing maltohexaose)

cysteine-type peptidase activity

endoribonuclease activity

lyase activity

GO_0030676

epidermal growth factor receptor binding

U1 snRNP binding

acetylcholine binding

acetylcholinesterase activity

amyloid-beta binding

carboxylic ester hydrolase activity

cholinesterase activity

collagen binding

hydrolase activity

laminin binding

serine hydrolase activity

activin binding

activin receptor activity, type I

transforming growth factor beta binding

transforming growth factor beta receptor activity, type I

transforming growth factor beta-activated receptor activity

type II transforming growth factor beta receptor binding

FK506 binding

macrolide binding

peptidyl-prolyl cis-trans isomerase activity

transforming growth factor beta receptor binding

type I transforming growth factor beta receptor binding

RNA polymerase II general transcription initiation factor activity

thyroid hormone receptor binding

vitamin D receptor binding

cyclin-dependent protein serine/threonine kinase inhibitor activity

cyclin binding

cyclin-dependent protein serine/threonine kinase activity

FBXO family protein binding

metalloendopeptidase inhibitor activity

endopeptidase activity

metalloaminopeptidase activity

metalloendopeptidase activity

cyclin-dependent protein serine/threonine kinase activator activity

ubiquitin binding

cyclin-dependent protein kinase activity

clathrin adaptor activity

low-density lipoprotein particle receptor binding

signal sequence binding

potassium channel inhibitor activity

sulfate binding

zymogen binding

actin filament binding

myosin II binding

phosphatidylinositol 3-kinase catalytic subunit binding

phosphatidylinositol-4,5-bisphosphate binding

myosin binding

structural constituent of cytoskeleton

MAP kinase kinase kinase activity

mitogen-activated protein kinase kinase binding

GO_0017034

protein tyrosine phosphatase activity

carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

amino acid binding

carbamoyl-phosphate synthase (ammonia) activity

GTPase regulator activity

phospholipase binding

GO_0048365

small GTPase binding

GTPase inhibitor activity

protein serine/threonine/tyrosine kinase activity

WW domain binding

ATPase-coupled cation transmembrane transporter activity

calcium ion transmembrane transporter activity

calcium transmembrane transporter activity, phosphorylative mechanism

nitric-oxide synthase inhibitor activity

PDZ domain binding

calmodulin-dependent protein kinase activity

endopeptidase inhibitor activity

chloride ion binding

interleukin-6 binding

calcium-dependent protein serine/threonine kinase activity

glutamate receptor binding

GTPase activating protein binding

kinase activity

cadmium ion binding

flavin adenine dinucleotide binding

FMN binding

heme binding

NADP binding

NADPH binding

NADPH-hemoprotein reductase activity

nitric-oxide synthase activity

oxidoreductase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

sodium channel regulator activity

dynein intermediate chain binding

dynein light intermediate chain binding

motor activity

3'-5' exonuclease activity

DNA-(apurinic or apyrimidinic site) endonuclease activity

double-stranded DNA 3'-5' exodeoxyribonuclease activity

double-stranded DNA exodeoxyribonuclease activity

double-stranded telomeric DNA binding

endodeoxyribonuclease activity

endonuclease activity

NF-kappaB binding

phosphodiesterase I activity

phosphoric diester hydrolase activity

site-specific endodeoxyribonuclease activity, specific for altered base

uracil DNA N-glycosylase activity

peptide disulfide oxidoreductase activity

protein disulfide oxidoreductase activity

protein-disulfide reductase activity

thioredoxin-disulfide reductase activity

calcium-dependent protein kinase C activity

GO_0017049

histone kinase activity (H3-T11 specific)

nuclear receptor coactivator activity

protein kinase C binding

Rho GDP-dissociation inhibitor binding

histone kinase activity (H3-T3 specific)

telomerase RNA binding

histone pre-mRNA DCP binding

U7 snRNA binding

translation elongation factor activity

isoprenoid binding

Rab geranylgeranyltransferase activity

A2A adenosine receptor binding

G protein-coupled receptor activity

G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential

glutamate receptor activity

neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

PLC activating G protein-coupled glutamate receptor activity

G protein-coupled glutamate receptor binding

molecular adaptor activity

1-phosphatidylinositol binding

co-SMAD binding

phosphatase binding

calcium-dependent cysteine-type endopeptidase activity

cytoskeletal protein binding

4 iron, 4 sulfur cluster binding

electron transfer activity

ferredoxin-thioredoxin reductase activity

GO_0030385

mRNA 5'-UTR binding

protein kinase A binding

retinoic acid binding

retinoic acid-responsive element binding

sequence-specific double-stranded DNA binding

translation repressor activity, mRNA regulatory element binding

DNA binding domain binding

LBD domain binding

peptide binding

retinoic acid receptor binding

arsenate reductase (azurin) activity

RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding

steroid hormone receptor activity

vitamin D response element binding

Rho GDP-dissociation inhibitor activity

lipopolysaccharide binding

thrombospondin receptor activity

histone methyltransferase binding

ionotropic glutamate receptor binding

gamma-catenin binding

vinculin binding

aspartic-type endopeptidase inhibitor activity

oligosaccharide binding

carboxypeptidase activity

metallocarboxypeptidase activity

ferredoxin hydrogenase activity

nickel cation binding

3 iron, 4 sulfur cluster binding

cytochrome-c3 hydrogenase activity

ribosome binding

toxic substance binding

2 iron, 2 sulfur cluster binding

ferredoxin-NADP+ reductase activity

NADPH-adrenodoxin reductase activity

superoxide-generating NADPH oxidase activator activity

superoxide-generating NAD(P)H oxidase activity

cyclin-dependent protein serine/threonine kinase regulator activity

MAP kinase kinase activity

GO_0017048

dystroglycan binding

laminin-1 binding

structural constituent of muscle

eukaryotic initiation factor 4E binding

translation repressor activity

eukaryotic initiation factor 4G binding

RNA 7-methylguanosine cap binding

translation initiation factor activity

serpin family protein binding

nucleosome binding

nuclear import signal receptor activity

nuclear localization sequence binding

microtubule plus-end binding

armadillo repeat domain binding

signaling adaptor activity

actin monomer binding

myosin heavy chain binding

tropomyosin binding

troponin I binding

succinate-CoA ligase (GDP-forming) activity

succinate-CoA ligase (ADP-forming) activity

protein tag

ubiquitin-like protein ligase binding

SUMO-specific isopeptidase activity

IgG binding

deoxyribonuclease inhibitor activity

protein folding chaperone

deoxyribonuclease activity

nuclease activity

phosphatase activator activity

TFIIF-class transcription factor complex binding

DNA helicase activity

interleukin-12 beta subunit binding

interleukin-12 receptor binding

interleukin-27 binding

cytokine binding

cytokine receptor activity

interleukin-12 alpha subunit binding

melatonin binding

cyclosporin A binding

heparan sulfate binding

unfolded protein binding

virion binding

enzyme activator activity

DNA replication origin binding

molybdopterin synthase activity

hemoglobin alpha binding

organic acid binding

oxygen binding

oxygen carrier activity

GO_0017016

farnesyltranstransferase activity

protein farnesyltransferase activity

acetylcholine receptor regulator activity

CAAX-protein geranylgeranyltransferase activity

protein geranylgeranyltransferase activity

acyl binding

G protein-coupled receptor binding

G-protein beta/gamma-subunit complex binding

proton-transporting ATP synthase activity, rotational mechanism

proton-transporting ATPase activity, rotational mechanism

1-phosphatidylinositol-3-kinase activity

proteasome binding

ubiquitin conjugating enzyme activity

1-alkyl-2-acetylglycerophosphocholine esterase activity

platelet-activating factor acetyltransferase activity

interferon-gamma receptor activity

interferon-gamma receptor binding

transcription regulator inhibitor activity

RNA polymerase II repressing transcription factor binding

molybdopterin cofactor binding

NADPH dehydrogenase activity

oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor

antisigma factor binding

enzyme inhibitor activity

helicase activity

single-stranded DNA binding

importin-alpha family protein binding

pigment binding

proteoglycan binding

aryl hydrocarbon receptor binding

obsolete thyroid hormone receptor coactivator activity

peptidase inhibitor activity

metallopeptidase activity

mRNA binding

RNA cap binding

snRNA binding

oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor

sulfurtransferase activity

beta-tubulin binding

protein kinase activator activity

acetylcholine receptor activator activity

ErbB-2 class receptor binding

voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels

telethonin binding

FATZ binding

LIM domain binding

titin Z domain binding

MHC class II protein complex binding

1-phosphatidylinositol-4-phosphate 3-kinase activity

phosphatidylinositol 3-kinase activity

phosphatidylinositol kinase activity

phosphatidylinositol-3,4-bisphosphate 5-kinase activity

endopeptidase activator activity

adenyl-nucleotide exchange factor activity

clathrin-uncoating ATPase activity

misfolded protein binding

anthranilate phosphoribosyltransferase activity

anthranilate synthase activity

GO_0005087

cysteine-type endopeptidase activity involved in apoptotic process

cysteine-type endopeptidase activity involved in apoptotic signaling pathway

cysteine-type endopeptidase activity involved in execution phase of apoptosis

death effector domain binding

ligand-gated sodium channel activity

beta-2 adrenergic receptor binding

phosphoserine residue binding

phosphothreonine residue binding

proline-rich region binding

RNA polymerase binding

sodium channel inhibitor activity

apolipoprotein binding

dynactin binding

histone-dependent DNA binding

lipoprotein particle binding

microtubule lateral binding

phosphatidylinositol binding

phosphatidylinositol bisphosphate binding

cis-trans isomerase activity

fibroblast growth factor binding

fibroblast growth factor-activated receptor activity

chemokine binding

fibroblast growth factor receptor binding

receptor-receptor interaction

interleukin-4 receptor activity

signaling receptor complex adaptor activity

four-way junction helicase activity

gamma-tubulin binding

H3 histone acetyltransferase activity

H4 histone acetyltransferase activity

phospholipase D activator activity

GO_0030306

phosphoprotein phosphatase activity

RNA polymerase II CTD heptapeptide repeat phosphatase activity

Tat protein binding

protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity

protein-phosphocysteine-mannitol phosphotransferase system transporter activity

protein-phosphocysteine-sugar phosphotransferase activity

caspase binding

cysteine-type endopeptidase inhibitor activity

ubiquitin conjugating enzyme binding

ubiquitin-like protein conjugating enzyme binding

ubiquitin-specific protease binding

BIR domain binding

non-membrane spanning protein tyrosine phosphatase activity

phosphatase activity

protein kinase A catalytic subunit binding

DNA end binding

DNA-dependent ATPase activity

U3 snoRNA binding

5'-deoxyribose-5-phosphate lyase activity

poly(A) binding

poly(U) RNA binding

translation activator activity

U4 snRNA binding

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

ferrous iron binding

superoxide dismutase activity

superoxide dismutase copper chaperone activity

actinin binding

RNA-binding transcription regulator activity

trans-activation response element binding

diamine N-acetyltransferase activity

lysine N-acetyltransferase activity, acting on acetyl phosphate as donor

tumor necrosis factor-activated receptor activity

DNA-binding transcription factor binding

C2H2 zinc finger domain binding

poly-pyrimidine tract binding

pre-mRNA 3'-splice site binding

G-protein alpha-subunit binding

insulin-like growth factor binding

insulin-like growth factor II binding

insulin-like growth factor-activated receptor activity

mannose binding

retromer complex binding

signaling receptor activity

beta-lactamase activity

insulin-activated receptor activity

insulin-like growth factor I binding

protein transporter activity

phosphatidylinositol-3,4-bisphosphate binding

phosphatidylinositol-3-phosphate binding

progesterone receptor binding

retinoid X receptor binding

melatonin receptor activity

NFAT protein binding

adenylate cyclase activity

calcium- and calmodulin-responsive adenylate cyclase activity

cAMP response element binding protein binding

acetylcholine receptor activity

chloride channel regulator activity

arrestin family protein binding

cAMP response element binding

RNA polymerase II transcription coactivator binding

GDP-dissociation inhibitor activity

G protein-coupled serotonin receptor binding

glucocorticoid receptor binding

Notch binding

ADP binding

rDNA binding

satellite DNA binding

choline binding

protein disulfide isomerase activity

fibrinogen binding

calcidiol binding

vitamin D binding

vitamin transmembrane transporter activity

cargo adaptor activity

polyubiquitin modification-dependent protein binding

deubiquitinase activator activity

histone butyryltransferase activity

histone crotonyltransferase activity

peptide butyryltransferase activity

pre-mRNA intronic binding

protein propionyltransferase activity

transferase activity, transferring acyl groups

cAMP-dependent protein kinase inhibitor activity

cAMP-dependent protein kinase activity

manganese ion binding

protein kinase A regulatory subunit binding

protein antigen binding

NEDD8 transferase activity

ubiquitin-ubiquitin ligase activity

MAP kinase activity

mitogen-activated protein kinase p38 binding

peptide antigen binding

troponin C binding

troponin T binding

ATP-dependent peptidase activity

thrombin-activated receptor activity

SNARE binding

actin-dependent ATPase activity

microfilament motor activity

myosin II heavy chain binding

myosin V binding

acetylcholine receptor binding

frizzled binding

heparan sulfate proteoglycan binding

peptidase activator activity

PTB domain binding

RAGE receptor binding

signaling receptor activator activity

AP-2 adaptor complex binding

cargo receptor activity

NAD+ binding

NAD-dependent protein deacetylase activity

protein-malonyllysine demalonylase activity

protein-succinyllysine desuccinylase activity

RNA polymerase I core binding

mineralocorticoid receptor binding

clathrin light chain binding

phosphatidylinositol-3,5-bisphosphate binding

myosin VI head/neck binding

U6 snRNA binding

integrase activity

beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity

lactose synthase activity

N-acetyllactosamine synthase activity

UDP-galactosyltransferase activity

transmembrane receptor protein tyrosine kinase activator activity

epidermal growth factor binding

epidermal growth factor-activated receptor activity

signal recognition particle binding

RNA polymerase III type 1 promoter sequence-specific DNA binding

RNA polymerase III type 2 promoter sequence-specific DNA binding

RNA polymerase III type 3 promoter sequence-specific DNA binding

TFIIIC-class transcription factor complex binding

type 2 fibroblast growth factor receptor binding

pre-mRNA branch point binding

glucose transmembrane transporter activity

protein-N(PI)-phosphohistidine-sugar phosphotransferase activity

protein-phosphocysteine-glucose phosphotransferase system transporter activity

polysaccharide binding

scavenger receptor activity

porin activity

U1 snRNA binding

U2 snRNA binding

U5 snRNA binding

7S RNA binding

aldehyde dehydrogenase (NAD+) activity

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity

NADH binding

mitochondrion targeting sequence binding

P-P-bond-hydrolysis-driven protein transmembrane transporter activity

endogenous lipid antigen binding

exogenous lipid antigen binding

lipopeptide binding

dynein heavy chain binding

phospholipase A2 inhibitor activity

sigma factor antagonist activity

sigma factor activity

bile acid binding

bile acid receptor activity

chenodeoxycholic acid binding

histidine phosphotransfer kinase activity

osmosensor activity

protein histidine kinase binding

transferase activity, transferring phosphorus-containing groups

cell adhesive protein binding involved in AV node cell-bundle of His cell communication

connexin binding

glucocorticoid receptor activity

steroid hormone binding

SNAP receptor activity

PRC1 complex binding

DNA topoisomerase binding

ciliary neurotrophic factor receptor activity

ciliary neurotrophic factor receptor binding

interleukin-11 binding

interleukin-11 receptor activity

interleukin-27 receptor activity

leukemia inhibitory factor receptor binding

fatty acid binding

NAD-dependent histone deacetylase activity

NAD-dependent histone deacetylase activity (H4-K16 specific)

protein serine/threonine phosphatase activity

myosin light chain kinase activity

ecdysone binding

iron ion binding

nitrate reductase activity

inositol 1,4,5 trisphosphate binding

ATPase activator activity

mRNA cap binding

mediator complex binding

calcitriol binding

lithocholic acid binding

lithocholic acid receptor activity

S100 protein binding

phosphatase regulator activity

myosin phosphatase activity

myosin-light-chain-phosphatase activity

WD40-repeat domain binding

GPI-linked ephrin receptor activity

nerve growth factor binding

nerve growth factor receptor activity

neurotrophin binding

neurotrophin p75 receptor binding

neurotrophin receptor activity

chemorepellent activity

neurotrophin TRKB receptor binding

axon guidance receptor activity

ephrin receptor activity

transmembrane-ephrin receptor activity

hepatocyte growth factor-activated receptor activity

beta-N-acetylglucosaminidase activity

lysozyme activity

monooxygenase activity

ribulose-bisphosphate carboxylase activity

cAMP binding

phosphatidylserine binding

transposase activity

voltage-gated calcium channel activity

high voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in AV node cell action potential

androgen binding

POU domain binding

RNA polymerase II general transcription initiation factor binding

endo-1,4-beta-xylanase activity

hydrolase activity, acting on glycosyl bonds

chitinase activity

histone acetyltransferase activity (H3-K14 specific)

ubiquitin activating enzyme activity

DNA binding, bending

RNA polymerase I general transcription initiation factor binding

RNA polymerase III general transcription initiation factor activity

RNA polymerase III transcription regulatory region sequence-specific DNA binding

TFIIA-class transcription factor complex binding

hyaluronic acid binding

antioxidant activity

enterobactin binding

exogenous protein binding

pyridoxal phosphate binding

ribonuclease activity

potassium channel regulator activity

small protein activating enzyme binding

SUMO-specific endopeptidase activity

IgA binding

3-oxoacyl-[acyl-carrier-protein] synthase activity

cytoskeletal anchor activity

ribosomal small subunit binding

nitrile hydratase activity

beta-aspartyl-peptidase activity

ABC-type vitamin B12 transporter activity

kinesin binding

MAP-kinase scaffold activity

histone deacetylase regulator activity

JUN kinase activity

Rab GDP-dissociation inhibitor activity

MAP kinase kinase kinase kinase activity

structural constituent of nuclear pore

guanylate kinase activity

phosphorylation-dependent protein binding

host cell surface binding

protein kinase C activity

serine-type carboxypeptidase activity

DNA N-glycosylase activity

G/U mismatch-specific uracil-DNA glycosylase activity

mismatched DNA binding

pyrimidine-specific mismatch base pair DNA N-glycosylase activity

sodium ion binding

SUMO binding

peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity

NEDD8-specific protease activity

thiol-dependent ubiquitin-specific protease activity

pectinesterase inhibitor activity

aspartyl esterase activity

pectinesterase activity

C3HC4-type RING finger domain binding

denatured protein binding

syntaxin binding

syntaxin-1 binding

protein transmembrane transporter activity

muscle alpha-actinin binding

hemoglobin binding

single-stranded RNA binding

lead ion binding

mercury ion binding

phospholipid scramblase activity

profilin binding

SUMO activating enzyme activity

ATP-dependent protein binding

NEDD8 activating enzyme activity

nucleoside binding

ankyrin binding

spectrin binding

transmembrane receptor protein tyrosine phosphatase activity

phosphatidylinositol phospholipase C activity

Lys48-specific deubiquitinase activity

ubiquitinyl hydrolase activity

single-stranded DNA endodeoxyribonuclease activity

TFIID-class transcription factor complex binding

G-rich strand telomeric DNA binding

lipid antigen binding

disulfide oxidoreductase activity

calcium-dependent phospholipid binding

phosphate ion binding

selenium binding

GDP-dissociation inhibitor binding

arachidonic acid binding

prostaglandin receptor activity

amylin binding

serine-type aminopeptidase activity

neurexin family protein binding

NAD+-diphthamide ADP-ribosyltransferase activity

rRNA binding

DNA primase activity

structural constituent of presynaptic active zone

nucleotidyltransferase activity

ubiquitin-like modifier activating enzyme activity

adenylylsulfate kinase activity

sulfate adenylyltransferase (ATP) activity

deoxyribonuclease I activity

bubble DNA binding

heteroduplex DNA loop binding

heterotrimeric G-protein binding

galactose binding

NAD+ ADP-ribosyltransferase activity

calcium channel activity

cation channel activity

glutamate binding

glutamate-gated calcium ion channel activity

glycine binding

ionotropic glutamate receptor activity

ligand-gated ion channel activity

ligand-gated ion channel activity involved in regulation of presynaptic membrane potential

neurotransmitter binding

NMDA glutamate receptor activity

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

voltage-gated cation channel activity

transferase activity, transferring pentosyl groups

Edg-2 lysophosphatidic acid receptor binding

sterol response element binding

arylsulfatase activity

cerebroside-sulfatase activity

sulfuric ester hydrolase activity

cupric ion binding

Formylglycine-generating oxidase activity

peptidyl-dipeptidase activity

host cell surface receptor binding

snoRNA binding

pseudouridine synthase activity

tRNA pseudouridine synthase activity

SUMO ligase activity

FHA domain binding

translation release factor activity, codon specific

protein methyltransferase activity

protein-(glutamine-N5) methyltransferase activity

protein-glutamine N-methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity

cellulose binding

hydrolase activity, hydrolyzing O-glycosyl compounds

interleukin-6 receptor activity

interleukin-6 receptor binding

leukemia inhibitory factor receptor activity

oncostatin-M receptor activity

ATP-gated ion channel activity

calcium-release channel activity

ryanodine-sensitive calcium-release channel activity

CH domain binding

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

potassium:proton antiporter activity

sodium:proton antiporter activity

sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential

solute:proton antiporter activity

ribonuclease A activity

ribonuclease inhibitor activity

nuclear export signal receptor activity

pre-miRNA binding

RISC complex binding

molybdenum ion binding

extracellularly ATP-gated cation channel activity

ligand-gated calcium channel activity

purinergic nucleotide receptor activity

methyltransferase activity

histone methyltransferase activity (H4-K20 specific)

lysine N-methyltransferase activity

TPR domain binding

acetyl-CoA C-acyltransferase activity

acetyl-CoA C-myristoyltransferase activity

cholesterol binding

cholesterol transfer activity

fatty-acyl-CoA binding

long-chain fatty acyl-CoA binding

oleic acid binding

phosphatidylcholine transfer activity

phosphatidylinositol transfer activity

propanoyl-CoA C-acyltransferase activity

propionyl-CoA C2-trimethyltridecanoyltransferase activity

sterol binding

peroxisome matrix targeting signal-1 binding

peroxisome membrane targeting sequence binding

peroxisome targeting sequence binding

protein sequestering activity

(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity

3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity

3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity

3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity

3-oxo-glutaryl-[acp] methyl ester reductase activity

3-oxo-pimeloyl-[acp] methyl ester reductase activity

3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity

[acyl-carrier-protein] S-acetyltransferase activity

[acyl-carrier-protein] S-malonyltransferase activity

enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity

myristoyl-[acyl-carrier-protein] hydrolase activity

oleoyl-[acyl-carrier-protein] hydrolase activity

palmitoyl-[acyl-carrier-protein] hydrolase activity

phosphopantetheine binding

holo-[acyl-carrier-protein] synthase activity

eukaryotic initiation factor eIF2 binding

protein kinase inhibitor activity

RING-like zinc finger domain binding

ubiquitin-protein transferase activator activity

small ribosomal subunit rRNA binding

structural constituent of ribosome

peptide alpha-N-acetyltransferase activity

ribosomal-protein-alanine N-acetyltransferase activity

transferase activity, transferring acyl groups other than amino-acyl groups

dopamine receptor binding

gamma-aminobutyric acid transmembrane transporter activity

protein-membrane adaptor activity

type 2 metabotropic glutamate receptor binding

3'-5'-exoribonuclease activity

exoribonuclease activity

poly(A)-specific ribonuclease activity

protein tyrosine kinase activator activity

proteasome-activating ATPase activity

myosin I binding

cargo receptor ligand activity

proteasome regulatory particle binding

F-box domain binding

double-stranded RNA binding

calcium-dependent protein serine/threonine phosphatase activity

biotin-[acetyl-CoA-carboxylase] ligase activity

SUMO conjugating enzyme activity

Roundabout binding

splicing factor binding

clathrin heavy chain binding

low-density lipoprotein particle binding

low-density lipoprotein particle receptor activity

very-low-density lipoprotein particle receptor activity

lipase binding

receptor antagonist activity

very-low-density lipoprotein particle receptor binding

penicillin binding

peptidoglycan glycosyltransferase activity

serine-type D-Ala-D-Ala carboxypeptidase activity

CCR chemokine receptor binding

CCR1 chemokine receptor binding

CCR5 chemokine receptor binding

chemokine activity

polypeptide N-acetylgalactosaminyltransferase activity

phospholipase C activity

cytochrome-c oxidase activity

alpha-2 macroglobulin receptor activity

apolipoprotein receptor activity

lipoprotein particle receptor binding

1-phosphatidylinositol-4-phosphate 5-kinase activity

beta-endorphin binding

ubiquitin-dependent protein binding

glucagon receptor binding

polynucleotide adenylyltransferase activity

mRNA (nucleoside-2'-O-)-methyltransferase activity

P-type divalent copper transporter activity

copper chaperone activity

acetylglucosaminyltransferase activity

beta-N-acetylhexosaminidase activity

N-acetyl-beta-D-galactosaminidase activity

complement binding

C5L2 anaphylatoxin chemotactic receptor binding

HLH domain binding

energy transducer activity

siderophore transmembrane transporter activity

siderophore uptake transmembrane transporter activity

phosphatidylinositol-5-phosphate binding

erythropoietin receptor binding

interleukin-3 receptor binding

GO_0017160

talin binding

acetylcholine receptor inhibitor activity

colicin transmembrane transporter activity

growth hormone receptor binding

histone kinase activity (H3-Y41 specific)

type 1 angiotensin receptor binding

tRNA binding

glutamate-tRNA ligase activity

glutamine-tRNA ligase activity

type I interferon receptor binding

type I interferon binding

type I interferon receptor activity

L27 domain binding

dioxygenase activity

structural constituent of postsynaptic density

G protein-coupled receptor kinase activity

rhodopsin kinase activity

exonuclease activity

GABA receptor binding

protein phosphatase regulator activity

arsenate reductase (thioredoxin) activity

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

platelet activating factor receptor activity

platelet-derived growth factor beta-receptor activity

platelet-derived growth factor binding

platelet-derived growth factor-activated receptor activity

demethylase activity

histone demethylase activity (H3-dimethyl-K4 specific)

histone demethylase activity (H3-K4 specific)

histone demethylase activity (H3-K9 specific)

telomeric repeat-containing RNA binding

translation factor activity, RNA binding

patched binding

cell-cell adhesion mediator activity

protein binding involved in heterotypic cell-cell adhesion

leucine zipper domain binding

CXCR chemokine receptor binding

neuropeptide hormone activity

pituitary adenylate cyclase activating polypeptide activity

pituitary adenylate cyclase-activating polypeptide receptor binding

G protein-coupled peptide receptor activity

neuropeptide binding

peptide hormone binding

vasoactive intestinal polypeptide receptor activity

microtubule-severing ATPase activity

cytochrome-c peroxidase activity

peroxidase activity

1-phosphatidylinositol 4-kinase activity

bacterial-type RNA polymerase core enzyme binding

calmodulin-dependent protein phosphatase activity

anaphase-promoting complex binding

inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity

phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity

phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity

phosphatidylinositol-3-phosphatase activity

protein tyrosine/serine/threonine phosphatase activity

phosphatidylinositol-3,4,5-trisphosphate binding

hydrolase activity, acting on ester bonds

myosin phosphatase regulator activity

protein phosphatase 1 binding

protein phosphatase inhibitor activity

K63-linked polyubiquitin modification-dependent protein binding

phospholipase A2 activator activity

peptide-methionine (R)-S-oxide reductase activity

peptide-methionine (S)-S-oxide reductase activity

filamin binding

bacterial-type cis-regulatory region sequence-specific DNA binding

DNA-binding transcription repressor activity

diacylglycerol binding

ribonuclease P activity

ATP-dependent microtubule motor activity, plus-end-directed

microtubule motor activity

apolipoprotein receptor binding

ISG15 transferase activity

HMG box domain binding

BMP receptor binding

structural constituent of virion

sumo-dependent protein binding

lipoprotein lipase activator activity

neuromedin K receptor binding

substance K receptor binding

substance P receptor binding

substance P receptor activity

tachykinin receptor activity

phosphatidic acid binding

NF-kappaB-inducing kinase activity

transcription antitermination factor activity, RNA binding

ATPase-coupled transmembrane transporter activity

transmembrane transporter activity

xenobiotic transmembrane transporter activity

cadherin binding involved in cell-cell adhesion

voltage-gated ion channel activity

voltage-gated sodium channel activity

histone kinase activity (H2B-S14 specific)

cuprous ion binding

siRNA binding

voltage-gated sodium channel activity involved in AV node cell action potential

voltage-gated sodium channel activity involved in bundle of His cell action potential

voltage-gated sodium channel activity involved in cardiac muscle cell action potential

voltage-gated sodium channel activity involved in Purkinje myocyte action potential

voltage-gated sodium channel activity involved in SA node cell action potential

advanced glycation end-product receptor activity

mitogen-activated protein kinase binding

transcription corepressor binding

chromo shadow domain binding

DNA translocase activity

interleukin-15 receptor binding

Toll-like receptor binding

Atg12 activating enzyme activity

Atg8 activating enzyme activity

phosphatidylethanolamine binding

arginine binding

tetrahydrobiopterin binding

transcription regulatory region RNA binding

bicarbonate transmembrane transporter activity

chloride channel activity

chloride channel inhibitor activity

chloride transmembrane transporter activity

intracellularly ATP-gated chloride channel activity

Sec61 translocon complex binding

TFIIE-class transcription factor complex binding

TFIIH-class transcription factor complex binding

mitochondrial transcription factor activity

deoxycytidyl transferase activity

ankyrin repeat binding

BAT3 complex binding

C-X-C chemokine binding

calcium-dependent protein kinase regulator activity

5'-3' exoribonuclease activity

neuropeptide receptor binding

G protein-coupled neurotensin receptor activity

cGMP binding

intracellular cAMP-activated cation channel activity

intracellular cGMP-activated cation channel activity

single-strand break-containing DNA binding

poly(G) binding

camphor 5-monooxygenase activity

beta-1 adrenergic receptor binding

D1 dopamine receptor binding

neuroligin family protein binding

P2Y1 nucleotide receptor binding

brain-derived neurotrophic factor binding

brain-derived neurotrophic factor-activated receptor activity

1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding

G protein-coupled serotonin receptor activity

Gq/11-coupled serotonin receptor activity

neurotransmitter receptor activity

serotonin binding

antiporter activity

iron-sulfur cluster binding

phosphoenolpyruvate-protein phosphotransferase activity

protein phosphorylated amino acid binding

histone methyltransferase activity (H3-K79 specific)

modification-dependent protein binding

C-C chemokine binding

C-C chemokine receptor activity

C-X-C chemokine receptor activity

C-X-C motif chemokine 12 receptor activity

myosin light chain binding

chemokine receptor binding

death receptor activity

CARD domain binding

JUN kinase kinase kinase activity

efflux transmembrane transporter activity

gap junction channel activity

gap junction channel activity involved in cell communication by electrical coupling

gap junction hemi-channel activity

glutathione transmembrane transporter activity

ion transmembrane transporter activity

histone methyltransferase activity (H3-K36 specific)

inositol 1,3,4,5 tetrakisphosphate binding

polynucleotide 5'-hydroxyl-kinase activity

large ribosomal subunit rRNA binding

lamin binding

phosphoadenylyl-sulfate reductase (thioredoxin) activity

histone demethylase activity (H3-K36 specific)

semaphorin receptor binding

hyalurononglucosaminidase activity

[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity

[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity

[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity

auxin binding

auxin receptor activity

inositol hexakisphosphate binding

G-protein gamma-subunit binding

RNA polymerase II complex recruiting activity

K48-linked polyubiquitin modification-dependent protein binding

nitrate reductase (cytochrome) activity

GABA-A receptor activity

GABA-gated chloride ion channel activity

inhibitory extracellular ligand-gated ion channel activity

cAMP-dependent protein kinase regulator activity

gastric inhibitory peptide receptor activity

m7G(5')pppN diphosphatase activity

m7G(5')pppN diphosphatase activator activity

retinol binding

ribonucleotide binding

small molecule binding

proteinase activated receptor binding

RNA polymerase I activity

SAM domain binding

MHC class I protein complex binding

translation release factor activity

oxysterol binding

phosphatidylinositol-4-phosphate binding

sterol transfer activity

sterol transporter activity

FFAT motif binding

rubredoxin-NAD+ reductase activity

rubredoxin-NADP+ reductase activity

maltodextrin transmembrane transporter activity

maltose transporting porin activity

ABC-type protein transporter activity

preprotein binding

tRNA (guanine-N7-)-methyltransferase activity

mRNA (guanine-N7-)-methyltransferase activity

mRNA guanylyltransferase activity

polynucleotide 5'-phosphatase activity

triphosphatase activity

GPI anchor binding

stem cell factor receptor activity

cellulase activity

exo-alpha-sialidase activity

RNA-dependent ATPase activity

NAD binding

NADP+ binding

3' overhang single-stranded DNA endodeoxyribonuclease activity

oxidized DNA binding

ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity

polynucleotide 3'-phosphatase activity

purine nucleotide binding

FAD binding

xanthine dehydrogenase activity

xanthine oxidase activity

peroxisome membrane class-1 targeting sequence binding

ferric iron binding

oxidoreductase activity, acting on metal ions

phosphodiesterase decapping endonuclease activity

catalytic activity

hedgehog family protein binding

glycosaminoglycan binding

glutaminase activity

imidazoleglycerol-phosphate synthase activity

DH domain binding

PH domain binding

structural molecule activity conferring elasticity

natural killer cell lectin-like receptor binding

toxin transmembrane transporter activity

type 1 fibroblast growth factor receptor binding

histone acetyltransferase activity (H4-K16 specific)

histone acetyltransferase activity (H4-K5 specific)

histone acetyltransferase activity (H4-K8 specific)

beta-fructofuranosidase activity

phosphatidylcholine binding

isopeptidase activity

Lys63-specific deubiquitinase activity

cellulose 1,4-beta-cellobiosidase activity

4-hydroxyphenylacetate decarboxylase activity

monophenol monooxygenase activity

magnesium-dependent protein serine/threonine phosphatase activity

cardiolipin binding

exopeptidase activity

oligopeptidase activity

interleukin-15 receptor activity

cytokine receptor binding

lipopolysaccharide immune receptor activity

Toll-like receptor 4 binding

NAD(P)+ nucleosidase activity

NAD+ nucleotidase, cyclic ADP-ribose generating

3'-flap endonuclease activity

gibberellin binding

G-protein beta-subunit binding

lipoic acid binding

lipoate-protein ligase activity

lipoyltransferase activity

high-density lipoprotein particle binding

reelin receptor activity

aminomethyltransferase activity

transaminase activity

hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity

transferase activity, transferring alkyl or aryl (other than methyl) groups

adrenomedullin binding

adrenomedullin receptor activity

calcitonin gene-related peptide receptor activity

calcitonin receptor activity

structural constituent of skin epidermis

netrin receptor activity

plus-end directed microfilament motor activity

exodeoxyribonuclease activity

histone demethylase activity (H3-K27 specific)

MHC class Ib protein binding, via antigen binding groove

cytoskeletal protein-membrane anchor activity

retinol dehydrogenase activity

7SK snRNA binding

5'-3' exodeoxyribonuclease activity

5'-3' exonuclease activity

protein serine/threonine kinase inhibitor activity

parathyroid hormone receptor binding

type 1 parathyroid hormone receptor binding

parathyroid hormone receptor activity

glucagon receptor activity

glucagon-like peptide 1 receptor activity

corticotropin-releasing hormone receptor 1 binding

mu-type opioid receptor binding

myosin head/neck binding

carbon-monoxide dehydrogenase (acceptor) activity

carbon-monoxide dehydrogenase (ferredoxin) activity

acetyl-CoA carboxylase activity

heme transmembrane transporter activity

6-phosphofructokinase activity

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity

GO_0017112

D5 dopamine receptor binding

aspartate carbamoyltransferase activity

dihydroorotase activity

interleukin-23 receptor binding

RNA polymerase core enzyme binding

RNA polymerase II C-terminal domain phosphoserine binding

toxin-antitoxin pair type II binding

interleukin-7 receptor activity

interleukin-7 receptor binding

interferon receptor activity

interleukin-20 binding

interleukin-22 receptor binding

complement component C1q complex binding

hormone binding

11-cis retinal binding

G protein-coupled photoreceptor activity

opsin binding

low voltage-gated calcium channel activity

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

histone serine kinase activity

D2 dopamine receptor binding

corticotropin-releasing hormone activity

corticotropin-releasing hormone receptor 2 binding

corticotrophin-releasing factor receptor activity

corticotropin-releasing hormone binding

corticotropin-releasing hormone receptor activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

acyl carrier activity

extracellular matrix structural constituent conferring tensile strength

oxoglutarate dehydrogenase (succinyl-transferring) activity

thiamine pyrophosphate binding

interleukin-18 receptor binding

neurotensin receptor activity, non-G protein-coupled

ABC-type peptide antigen transporter activity

TAP complex binding

TAP1 binding

TAP2 binding

alkanal monooxygenase (FMN-linked) activity

phospholipase activator activity

RNA NAD-cap (NAD-forming) hydrolase activity

RNA pyrophosphohydrolase activity

IgG receptor activity

CTP binding

dATP binding

sulfonylurea receptor binding

UTP binding

interleukin-22 binding

interleukin-22 receptor activity

inward rectifier potassium channel activity

acetate-CoA ligase activity

propionate-CoA ligase activity

glutathione binding

glutathione transferase activity

glutathione peroxidase activity

adenylyl-sulfate reductase activity

ATP-dependent microtubule motor activity, minus-end-directed

aminopeptidase activity

kininogen binding

double-stranded methylated DNA binding

JUN kinase phosphatase activity

MAP kinase tyrosine/serine/threonine phosphatase activity

protein tyrosine/threonine phosphatase activity

2-oxoglutarate-dependent dioxygenase activity

L-ascorbic acid binding

peptidyl-proline 4-dioxygenase activity

peptidyl-proline dioxygenase activity

tRNA-intron endonuclease activity

cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

alpha-2A adrenergic receptor binding

omega peptidase activity

extracellular matrix protein binding

opsonin binding

abscisic acid binding

CTPase activity

nucleoside-triphosphatase activity

RNA stem-loop binding

RNA strand annealing activity

3',5'-cyclic-GMP phosphodiesterase activity

3',5'-cyclic-nucleotide phosphodiesterase activity

protein adenylyltransferase activity

protein guanylyltransferase activity

single-stranded telomeric DNA binding

cobalamin binding

D-ornithine 4,5-aminomutase activity

dimethylallyltranstransferase activity

histone demethylase activity (H4-K20 specific)

ligand-activated transcription factor activity

kringle domain binding

ribonuclease P RNA binding

MHC class II receptor activity

macrophage colony-stimulating factor receptor binding

ribonucleoside binding

transporter activity

hydrogenase (acceptor) activity

prolactin receptor activity

prolactin receptor binding

rRNA N-glycosylase activity

amylin receptor activity

calcitonin gene-related peptide binding

cholesterol monooxygenase (side-chain-cleaving) activity

piRNA binding

fumarate transmembrane transporter activity

L-aspartate transmembrane transporter activity

secondary active sulfate transmembrane transporter activity

succinate transmembrane transporter activity

ubiquitin-like protein binding

hydro-lyase activity

complement receptor activity

interleukin-28 receptor binding

alkylglycerophosphoethanolamine phosphodiesterase activity

type 2A serotonin receptor binding

CX3C chemokine receptor binding

CXCR1 chemokine receptor binding

D-glucosamine PTS permease activity

methyl indole-3-acetate esterase activity

protein C-terminal carboxyl O-methyltransferase activity

protein C-terminal leucine carboxyl O-methyltransferase activity

DNA ligase (ATP) activity

DNA ligase activity

protein N-acetylglucosaminyltransferase activity

protein O-GlcNAc transferase activity

L-methionine-(S)-S-oxide reductase activity

glycerone kinase activity

phosphoenolpyruvate-glycerone phosphotransferase activity

sphingomyelin phosphodiesterase activator activity

transcription elongation regulator activity

protein prenyltransferase activity

BMP receptor activity

BMP binding

interleukin-4 receptor binding

inositol phosphate phosphatase activity

inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity

inositol-1,4,5-trisphosphate 5-phosphatase activity

inositol-polyphosphate 5-phosphatase activity

phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

G-protein activated inward rectifier potassium channel activity

somatostatin receptor binding

synaptic receptor adaptor activity

extracellularly glutamate-gated ion channel activity

kainate selective glutamate receptor activity

bile acid transmembrane transporter activity

granulocyte colony-stimulating factor receptor binding

protein-glutaryllysine deglutarylase activity

coreceptor activity involved in canonical Wnt signaling pathway

coreceptor activity involved in Wnt signaling pathway

kinase inhibitor activity

Wnt-activated receptor activity

Wnt-protein binding

gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling

gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling

AP-1 adaptor complex binding

AF-2 domain binding

cation transmembrane transporter activity

excitatory extracellular ligand-gated ion channel activity

extracellular ligand-gated ion channel activity

temperature-gated ion channel activity

DNA (cytosine-5-)-methyltransferase activity

DNA-methyltransferase activity

DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates

structural constituent of presynapse

ribosomal protein S6 kinase activity

N-acetyltransferase activity

peptidyl-lysine acetyltransferase activity

MAP kinase phosphatase activity

interleukin-21 receptor activity

phosphatidylinositol phosphate binding

protein ADP-ribosylase activity

ATPase inhibitor activity

guanylate cyclase activity

5'-flap endonuclease activity

flap endonuclease activity

histone deacetylase activity

NAD-dependent histone deacetylase activity (H3-K14 specific)

potassium ion binding

protein deacetylase activity

steroid hormone receptor binding

protein serine/threonine phosphatase inhibitor activity

ribonuclease E activity

iron chaperone activity

ferric iron transmembrane transporter activity

amidase activity

acylphosphatase activity

carboxyl- or carbamoyltransferase activity

carbon monoxide binding

carbon dioxide binding

fructose-6-phosphate binding

glucokinase activity

glucose binding

chloramphenicol O-acetyltransferase activity

thioredoxin peroxidase activity

mRNA methyltransferase activity

N(6)-L-threonylcarbamoyladenine synthase activity

deacetylase activity

NAD(P)+-protein-arginine ADP-ribosyltransferase activity

NAD-dependent histone deacetylase activity (H3-K9 specific)

cohesin ATPase activity

topological DNA entrapment activity

pre-mRNA binding

GAF domain binding

POZ domain binding

bradykinin receptor binding

metallodipeptidase activity

tripeptidyl-peptidase activity

mRNA 3'-UTR AU-rich region binding

S-adenosyl-L-methionine binding

telomerase activity

telomerase RNA reverse transcriptase activity

template-free RNA nucleotidyltransferase

histone kinase activity (H3-S10 specific)

ubiquitin-protein transferase inhibitor activity

ubiquitin ligase activator activity

G-quadruplex DNA binding

methionine-tRNA ligase activity

phosphorylated histone binding

cyclic nucleotide binding

recombination hotspot binding

selenocysteine insertion sequence binding

DNA topoisomerase activity

DNA topoisomerase type I (single strand cut, ATP-independent) activity

photoreceptor activity

pullulanase activity

adenylate kinase activity

AP-3 adaptor complex binding

BLOC-2 complex binding

excinuclease ABC activity

lipid phosphatase activity

O-methyltransferase activity

RNA methyltransferase activity

store-operated calcium channel activity

ferredoxin-NAD+ reductase activity

intracellular cyclic nucleotide activated cation channel activity

cyclic-di-GMP binding

single-stranded DNA 3'-5' exodeoxyribonuclease activity

rRNA (cytosine-C5-)-methyltransferase activity

type 2 angiotensin receptor binding

interleukin-1 binding

interleukin-1 receptor activity

interleukin-1, type I, activating receptor activity

interleukin-1 receptor binding

NEDD8 conjugating enzyme activity

iodide peroxidase activity

L-ascorbate oxidase activity

L-ascorbate peroxidase activity

odorant binding

carbohydrate response element binding

delayed rectifier potassium channel activity

MHC class I receptor activity

histone demethylase activity (H3-monomethyl-K4 specific)

fucose binding

sialic acid binding

nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity

cellulose synthase (UDP-forming) activity

riboflavin transmembrane transporter activity

tryptophan synthase activity

bone sialoprotein binding

dynein light chain binding

protein phosphatase 5 binding

serine-type exopeptidase activity

dopamine binding

tyrosine 3-monooxygenase activity

nicotinate-nucleotide adenylyltransferase activity

telomerase inhibitor activity

pattern recognition receptor activity

peptidoglycan binding

interleukin-33 binding

interleukin-33 receptor activity

interleukin-33 receptor binding

protein-hormone receptor activity

peptide-glutamate-N-acetyltransferase activity

peptide-serine-N-acetyltransferase activity

acetyltransferase activator activity

neurotrophin TRKC receptor binding

fructokinase activity

mannokinase activity

serine O-acetyltransferase activity

cysteine synthase activity

L-cysteine desulfhydrase activity

ISG15-specific protease activity

3'-5' DNA helicase activity

complement component C3b binding

magnesium ion transmembrane transporter activity

G protein-coupled GABA receptor activity

G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

annealing helicase activity

beta-3 adrenergic receptor binding

obsolete electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity

NAD(P)+ transhydrogenase (AB-specific) activity

hydrolase activity, hydrolyzing N-glycosyl compounds

RS domain binding

glutathione hydrolase activity

hypoglycin A gamma-glutamyl transpeptidase activity

leukotriene C4 gamma-glutamyl transferase activity

histone kinase activity (H2A-T120 specific)

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

penicillin amidase activity

sulfite oxidase activity

iron ion transmembrane transporter inhibitor activity

NAD glycohydrolase activity

poly-ADP-D-ribose binding

rRNA (guanine) methyltransferase activity

dipeptidyl-peptidase activity

delta-catenin binding

interleukin-18 binding

interleukin-18 receptor activity

methylmalonyl-CoA mutase activity

P-TEFb complex binding

RNA polymerase I general transcription initiation factor activity

RNA polymerase II-specific DNA-binding transcription factor binding

neuregulin binding

neuregulin receptor activity

3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity

3-phosphoinositide-dependent protein kinase activity

granulocyte macrophage colony-stimulating factor receptor binding

adrenomedullin receptor binding

DNA hairpin binding

ubiquitin-like protein transferase activity

phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity

phosphatidylinositol-4-phosphate phosphatase activity

transferase activity, transferring glycosyl groups

calcium oxalate binding

3'-5' RNA helicase activity

MIT domain binding

translation regulator activity

modified amino acid binding

heterocyclic compound binding

JUN kinase kinase activity

intraciliary transport particle B binding

collagen binding involved in cell-matrix adhesion

UDP-xylosyltransferase activity

glycosylation-dependent protein binding

cytoskeletal regulatory protein binding

oxidoreductase activity, acting on iron-sulfur proteins as donors

channel regulator activity

histone methyltransferase activity (H4-R3 specific)

histone-arginine N-methyltransferase activity

protein-arginine N-methyltransferase activity

protein-arginine omega-N symmetric methyltransferase activity

bacterial-type RNA polymerase holo enzyme binding

euchromatin binding

kinetochore binding

3-phosphoinositide-dependent protein kinase binding

phosphatidic acid transfer activity

NAD DNA ADP-ribosyltransferase activity

nitric oxide reductase activity

tubulin deacetylase activity

pyrimidine nucleotide binding

histone kinase activity

beta-catenin destruction complex binding

chlorophyll binding

interleukin-5 receptor binding

syndecan binding

crossover junction endodeoxyribonuclease activity

double-stranded DNA endodeoxyribonuclease activity

ornithine decarboxylase inhibitor activity

ornithine decarboxylase activity

protein-propionyllysine depropionylase activity

proline-tRNA ligase activity

histone demethylase activity (H3-trimethyl-K4 specific)

carbohydrate transmembrane transporter activity

maltose binding

tRNA (uracil) methyltransferase activity

adenosine receptor binding

U6atac snRNA binding

N-terminal protein N-methyltransferase activity

sequence-specific mRNA binding

translation termination factor activity

retroviral 3' processing activity

anion:anion antiporter activity

oxalate transmembrane transporter activity

sulfate transmembrane transporter activity

cyclin-dependent protein kinase activating kinase activity

opioid peptide activity

opioid receptor binding

diacylglycerol kinase activity

lipid kinase activity

NAD+ kinase activity

lipoate synthase activity

lipoyl synthase activity (acting on glycine-cleavage complex H protein

lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)

alpha-glucosidase activity

glucan 1,3-alpha-glucosidase activity

glucosidase activity

light-activated ion channel activity

myosin III binding

glucosyltransferase activity

UDP-glucosyltransferase activity

AMPA glutamate receptor activity

G protein-coupled adenosine receptor activity

endothelin A receptor binding

endothelin B receptor binding

endothelin receptor activity

ubiquitin-like protein-specific protease activity

peptide receptor activity

isocitrate dehydrogenase (NAD+) activity

microtubule minus-end binding

8-hydroxy-2'-deoxyguanosine DNA binding

G-rich single-stranded DNA binding

telomeric D-loop binding

sulfite reductase (ferredoxin) activity

sulfite reductase activity

ADP-ribosyl-[dinitrogen reductase] hydrolase activity

ubiquitin-protein transferase regulator activity

calcitonin binding

nucleosome-dependent ATPase activity

mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity

mRNA (N6-adenosine)-methyltransferase activity

interleukin-10 binding

interleukin-10 receptor activity

elongation factor-2 kinase activity

cysteine-type carboxypeptidase activity

peptide-aspartate beta-dioxygenase activity

peptidyl-aspartic acid 3-dioxygenase activity

retinal binding

retinol transmembrane transporter activity

hydroxymethylglutaryl-CoA synthase activity

fucosyltransferase activity

peptide-O-fucosyltransferase activity

endoplasmic reticulum signal peptide binding

lipoteichoic acid immune receptor activity

long-chain fatty acid transporter activity

oxidised low-density lipoprotein particle receptor activity

short-chain fatty acid transmembrane transporter activity

prenylated protein tyrosine phosphatase activity

double-stranded DNA helicase activity

glycylpeptide N-tetradecanoyltransferase activity

myristoyltransferase activity

electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity

oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor

DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity

latrotoxin receptor activity

copper ion transmembrane transporter activity

copper-dependent protein binding

metallochaperone activity

DNA-binding transcription activator activity

5'-tyrosyl-DNA phosphodiesterase activity

tyrosyl-RNA phosphodiesterase activity

single base insertion or deletion binding

interleukin-3 receptor activity

carboxy-lyase activity

transcription antitermination factor activity, DNA binding

palmitoyltransferase activity

protein-cysteine S-palmitoyltransferase activity

BH4 domain binding

RNA cap 4 binding

aminoacyl-tRNA ligase activity

threonine-tRNA ligase activity

protein-glutamate O-methyltransferase activity

autoinducer-2 kinase activity

phosphotransferase activity, alcohol group as acceptor

heterochromatin-nuclear membrane anchor activity

centromere-nuclear envelope anchor activity

centromeric DNA binding

chemokine (C-C motif) ligand 5 binding

chemokine receptor activity

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

RNA NAD-cap (NMN-forming) hydrolase activity

diaminopimelate epimerase activity

potassium:proton exchanging ATPase activity

[phosphorylase] phosphatase activity

glycogen binding

oxidoreductase activity, acting on CH-OH group of donors

tumor necrosis factor receptor superfamily binding

spindle pole body-nuclear membrane anchor activity

type II activin receptor binding

histone demethylase activity (H3-R2 specific)

histone demethylase activity (H4-R3 specific)

oxidative RNA demethylase activity

peptidyl-lysine 5-dioxygenase activity

D-alanyl carrier activity

DNA secondary structure binding

structural constituent of postsynapse

succinate dehydrogenase (ubiquinone) activity

NAD+-protein-arginine ADP-ribosyltransferase activity

NADP+-protein-arginine ADP-ribosyltransferase activity

ADP-ribosylarginine hydrolase activity

leptin receptor activity

erythropoietin receptor activity

minus-end directed microfilament motor activity

1-acyl-2-lysophosphatidylserine acylhydrolase activity

lipase activity

lipoprotein lipase activity

phosphatidylserine 1-acylhydrolase activity

phospholipase A1 activity

phospholipase activity

triglyceride binding

triglyceride lipase activity

chylomicron binding

neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

protein xylosyltransferase activity

beta-ketoacyl-acyl-carrier-protein synthase III activity

somatostatin receptor activity

histone acetyltransferase activity (H3-K56 specific)

lipoprotein releasing activity

pre-mRNA intronic pyrimidine-rich binding

snRNA stem-loop binding

CCR4 chemokine receptor binding

chemokine receptor antagonist activity

receptor signaling protein tyrosine kinase activator activity

guanylate cyclase activator activity

carbon-nitrogen ligase activity on lipid II

calcium ion sensor activity

syntaxin-3 binding

5'-3' DNA helicase activity

5'-3' DNA/RNA helicase activity

5'-3' RNA helicase activity

transcription termination site sequence-specific DNA binding

glycolipid transfer activity

protein-glutamine gamma-glutamyltransferase activity

exon-exon junction complex binding

ribosomal large subunit binding

interferon-gamma binding

ganglioside GT1b binding

methylarsonite methyltransferase activity

site-specific DNA-methyltransferase (adenine-specific) activity

rRNA (adenine-N6-)-methyltransferase activity

UFM1 activating enzyme activity

sulfatide binding

NADH dehydrogenase (ubiquinone) activity

quinone binding

exodeoxyribonuclease III activity

aspartic-type peptidase activity

glutamic-type peptidase activity

L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity

ceramide 1-phosphate transfer activity

lipid transporter activity

phospholipid transfer activity

phospholipid transporter activity

triglyceride transfer activity

procollagen-proline 4-dioxygenase activity

structural constituent of postsynaptic actin cytoskeleton

protein-histidine N-methyltransferase activity

ferroxidase activity

oxidoreductase activity, acting on metal ions, oxygen as acceptor

structural constituent of postsynaptic specialization

activin receptor binding

tRNA 2'-O-methyltransferase activity

tRNA methyltransferase activity

aldehyde oxygenase (deformylating) activity

octadecanal decarbonylase activity

blue light photoreceptor activity

NAD(P)H oxidase H2O2-forming activity

calcium-induced calcium release activity

organic cyclic compound binding

suramin binding

cyclic-GMP-AMP binding

anti-sigma factor antagonist activity

dinitrosyl-iron complex binding

coenzyme-B sulfoethylthiotransferase activity

calcitonin receptor binding

preribosome binding

aromatic amino acid transmembrane transporter activity

calcium:sodium antiporter activity

L-alanine transmembrane transporter activity

L-leucine transmembrane transporter activity

neutral amino acid transmembrane transporter activity

transferrin receptor activity

phosphocholine transferase activity

structural constituent of cell wall

3'-flap-structured DNA binding

forked DNA-dependent helicase activity

telomeric G-quadruplex DNA binding

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