iPPI - DB
iPPI-DB is a database of modulators of protein-protein interactions. It contains
exclusively small molecules and therefore no peptides. The data are retrieved from
the literature either peer reviewed scientific articles or world patents.
A large variety of data is stored within iPPI-DB: structural, pharmacological,
binding and activity profile, pharmacokinetic and cytotoxicity when available, as
well as some data about the PPI targets themselves.
Latest publications
The iPPI-DB initiative: a community-centered database of protein–protein
interaction modulators
Torchet R, Druart K, Checa Ruano L, Moine-Franel A, Borges H, Doppelt-Azeroual O, Brancotte B, Mareuil F, Nilges M, Ménager H, Sperandio O
Bioinformatics, 2021;, btaa1091. doi: 10.1093/bioinformatics/btaa1091. Epub 2021 Jan 8.
Torchet R, Druart K, Checa Ruano L, Moine-Franel A, Borges H, Doppelt-Azeroual O, Brancotte B, Mareuil F, Nilges M, Ménager H, Sperandio O
Bioinformatics, 2021;, btaa1091. doi: 10.1093/bioinformatics/btaa1091. Epub 2021 Jan 8.
Redesign of iPPI-DB, a database for modulators of Protein-Protein
Interactions
Torchet R, Moine-Franel A, Borges H, Brancotte B, Doppelt-Azeroual O, Mareuil F, Ménager H, Sperandio O.
JOBIM 2019 - Talk presentation
Torchet R, Moine-Franel A, Borges H, Brancotte B, Doppelt-Azeroual O, Mareuil F, Ménager H, Sperandio O.
JOBIM 2019 - Talk presentation
iPPI-DB: an online database of modulators of protein-protein
interactions.
Labbé CM, Kuenemann MA, Zarzycka B, Vriend G, Nicolaes GA, Lagorce D, Miteva MA, Villoutreix BO, Sperandio O.
Nucleic Acids Res. 2016 Jan 4;44(D1):D542-7. doi: 10.1093/nar/gkv982. Epub 2015 Oct 1.
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Labbé CM, Kuenemann MA, Zarzycka B, Vriend G, Nicolaes GA, Lagorce D, Miteva MA, Villoutreix BO, Sperandio O.
Nucleic Acids Res. 2016 Jan 4;44(D1):D542-7. doi: 10.1093/nar/gkv982. Epub 2015 Oct 1.
Compounds
Protein Interaction Explorer (PIE)
Compounds
Pockets