Contributors
Luis Checa Ruano
Published contributions number
- 13 publications
- 0 patents
- 184 compounds
- 314 pharmacological data
- 13 PPI targets
Scientific publications and patents
- Vidler Lewis R., Filippakopoulos Panagis, Fedorov Oleg, Picaud Sarah, Martin Sarah, Tomsett Michael, Woodward Hannah, Brown Nathan, Knapp Stefan, Hoelder Swen. . Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening Journal of Medicinal Chemistry.
- Zhang Guangtao, Plotnikov Alexander N., Rusinova Elena, Shen Tong, Morohashi Keita, Joshua Jennifer, Zeng Lei, Mujtaba Shiraz, Ohlmeyer Michael, Zhou Ming-Ming. . Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains Journal of Medicinal Chemistry.
- Rew Yosup, Sun Daqing, Gonzalez-Lopez De Turiso Felix, Bartberger Michael D., Beck Hilary P., Canon Jude, Chen Ada, Chow David, Deignan Jeffrey, Fox Brian M., Gustin Darin, Huang Xin, Jiang Min, Jiao Xianyun, Jin Lixia, Kayser Frank, Kopecky David J., Li Yihong, Lo Mei-Chu, Long Alexander M., Michelsen Klaus, Oliner Jonathan D., Osgood Tao, Ragains Mark, Saiki Anne Y., Schneider Steve, Toteva Maria, Yakowec Peter, Yan Xuelei, Ye Qiuping, Yu Dongyin, Zhao Xiaoning, Zhou Jing, Medina Julio C., Olson Steven H.. . Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction Journal of Medicinal Chemistry.
- Millan David S., Kayser-Bricker Katherine J., Martin Matthew W., Talbot Adam C., Schiller Shawn E. R., Herbertz Torsten, Williams Grace L., Luke George P., Hubbs Stephen, Alvarez Morales Monica A., Cardillo Daniel, Troccolo Paul, Mendes Rachel L., McKinnon Crystal. . Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains ACS Medicinal Chemistry Letters.
- Gonzalez-Lopez de Turiso Felix, Sun Daqing, Rew Yosup, Bartberger Michael D., Beck Hilary P., Canon Jude, Chen Ada, Chow David, Correll Tiffany L., Huang Xin, Julian Lisa D., Kayser Frank, Lo Mei-Chu, Long Alexander M., McMinn Dustin, Oliner Jonathan D., Osgood Tao, Powers Jay P., Saiki Anne Y., Schneider Steve, Shaffer Paul, Xiao Shou-Hua, Yakowec Peter, Yan Xuelei, Ye Qiuping, Yu Dongyin, Zhao Xiaoning, Zhou Jing, Medina Julio C., Olson Steven H.. . Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors Journal of Medicinal Chemistry.
- Theodoulou Natalie H., Bamborough Paul, Bannister Andrew J., Becher Isabelle, Bit Rino A., Che Ka Hing, Chung Chun-wa, Dittmann Antje, Drewes Gerard, Drewry David H., Gordon Laurie, Grandi Paola, Leveridge Melanie, Lindon Matthew, Michon Anne-Marie, Molnar Judit, Robson Samuel C., Tomkinson Nicholas C. O., Kouzarides Tony, Prinjha Rab K., Humphreys Philip G.. . Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition Journal of Medicinal Chemistry.
- Zhao Hongtao, Gartenmann Lisa, Dong Jing, Spiliotopoulos Dimitrios, Caflisch Amedeo. . Discovery of BRD4 bromodomain inhibitors by fragment-based high-throughput docking Bioorganic & Medicinal Chemistry Letters.
- Ayoub AM, Hawk LML, Herzig RJ, Jiang J, Wisniewski AJ, Gee CT, Zhao P, Zhu JY, Berndt N, Offei-Addo NK, Scott TG, Qi J, Bradner JE, Ward TR, Schönbrunn E, Georg GI, Pomerantz WCK. . BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen. Journal of medicinal chemistry.
- Crawford Terry D., Tsui Vickie, Flynn E. Megan, Wang Shumei, Taylor Alexander M., Côté Alexandre, Audia James E., Beresini Maureen H., Burdick Daniel J., Cummings Richard, Dakin Les A., Duplessis Martin, Good Andrew C., Hewitt Michael C., Huang Hon-Ren, Jayaram Hariharan, Kiefer James R., Jiang Ying, Murray Jeremy, Nasveschuk Christopher G., Pardo Eneida, Poy Florence, Romero F. Anthony, Tang Yong, Wang Jian, Xu Zhaowu, Zawadzke Laura E., Zhu Xiaoyu, Albrecht Brian K., Magnuson Steven R., Bellon Steve, Cochran Andrea G.. . Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains Journal of Medicinal Chemistry.
- Baud Matthias G. J., Lin-Shiao Enrique, Zengerle Michael, Tallant Cynthia, Ciulli Alessio. . New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition Journal of Medicinal Chemistry.
- Chung Chun-wa, Coste Hervé, White Julia H., Mirguet Olivier, Wilde Jonathan, Gosmini Romain L., Delves Chris, Magny Sylvie M., Woodward Robert, Hughes Stephen A., Boursier Eric V., Flynn Helen, Bouillot Anne M., Bamborough Paul, Brusq Jean-Marie G., Gellibert Françoise J., Jones Emma J., Riou Alizon M., Homes Paul, Martin Sandrine L., Uings Iain J., Toum Jérôme, Clément Catherine A., Boullay Anne-Bénédicte, Grimley Rachel L., Blandel Florence M., Prinjha Rab K., Lee Kevin, Kirilovsky Jorge, Nicodeme Edwige. . Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains Journal of Medicinal Chemistry.
- Bista Michal, Wolf Siglinde, Khoury Kareem, Kowalska Kaja, Huang Yijun, Wrona Ewa, Arciniega Marcelino, Popowicz Grzegorz M., Holak Tad A., Dömling Alexander. . Transient Protein States in Designing Inhibitors of the MDM2-p53 Interaction Structure.
- Ma Yao, Lahue Brian R., Gibeau Craig R., Shipps Gerald W., Bogen Stéphane L., Wang Yaolin, Guo Zhuyan, Guzi Timothy J.. . Pivotal Role of an Aliphatic Side Chain in the Development of an HDM2 Inhibitor ACS Medicinal Chemistry Letters.